by Bruce Sylvester – The presence of the single nucleotide polymorphism (SNP) rs895374, located in UbcH7, an E2 ligase conducting neddylation of HECT E3 ligases involved in EGFR… read more.
by Bruce Sylvester – Intermittent strategies for delivering systemic treatment in metastatic colorectal cancer show no clinically significant superiority in overall survival rates when compared to continuous delivery,… read more.
This year saw the first of an exciting new style of conference. The Urology QT Conference was based on a ‘Question Time’ format that encouraged lively debate and… read more.
by Bruce Sylvester – In the FIRE 3 trial, clinicians favored the use of second-line antibodies in patients with KRAS wild-type metastatic colorectal cancer (mCRC) with shorter first-line progression free… read more.
by Bruce Sylvester – KRAS exon 2 mutations are independent predictors of time to recurrence or disease-free survival among patients with stage III distal colon cancer who are receiving… read more.
by Bruce Sylvester – Metastatic colorectal cancer patients who achieved early response to first-line chemotherapy also achieved significantly higher rates of prolonged survival, compared to patients who did… read more.
by Bruce Sylvester – Survival based on primary site of disease is not significantly different among metastatic colorectal cancer patients, Australian researchers reported in a poster presentation at… read more.
Adapted from Abstract 3506, which was submitted to ASCO Congress 2014 Treatment outcome according to tumour RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized… read more.
by Bruce Sylvester – Metformin therapy at 500 twice daily (BID) is not protective against heart failure in non-diabetic patients following a heart attack, researchers reported on March… read more.
by Bruce Sylvester – Chronic obstructive pulmonary disease (COPD) patients involved in moderate to vigorous physical activity are at a lower risk of hospital readmission within 30 days… read more.
by Bruce Sylvester – Researchers from the Joints on Glucosamine study (JOG) report that oral glucosamine supplementation does not reduce knee cartilage deterioration in osteoarthritis or improve knee… read more.
by Bruce Sylvester – Using ordinary instrumentation plus a computer during nocturnal insulin delivery, scientists have found a method to predict and prevent dangerously low overnight blood sugars… read more.
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